Abstract:

About Helicobacter pylori（Hp） infection，there is the view that Hp direct interference metabolism or indirect chronic inflammation may be associated with many diseases，and some even suggest that some of the protein composition of Hp or Hp be as a treatment for some diseases，such as asthma and obesity. However， based on the studies on the data about gastroesophageal reflux disease and abnormal immune disease，such as asthma，food allergies，inflammatory bowel disease（IBD） and obesity，there is no evidence showing that Hp is good for the human body. Therefore，for Hp infection- related diseases，pediatricians should give active treatment and strengthen research in order to cope with the rising Hp resistance and treatment failure rate.

Key words: Helicobacter pylori, infection, gastroesophageal reflux, asthma, allergy, obesity

摘要：

关于幽门螺杆菌（Hp）感染，有观点认为Hp直接干扰代谢或间接慢性炎症作用可与多种疾病相关，甚至提出Hp或Hp的某些蛋白成分可作为治疗一些疾病如哮喘、肥胖等方法。但是，对于胃食管反流病、免疫异常疾病（如哮喘、食物过敏、炎症性肠病）和肥胖等现有资料研究发现，没有证据证明Hp对人体的“有益性”。所以，对于Hp感染相关性疾病需积极予以根治，并加强研究，应对日益上升的Hp耐药性和治疗失败率。

关键词: 幽门螺杆菌, 感染, 胃食管反流, 哮喘, 过敏, 肥胖