Abstract:

Coronary artery lesion（CAL） is the most important complication of Kawasaki disease，and has become the leading cause of acquired heart disease in childhood in developed countries. This paper describes the diagnosis and evaluation of CAL in children with Kawasaki disease，and the management and follow-up of CAL. It focuses on how to use echocardiography to detect the coronary arteries in children with Kawasaki disease and how to evaluate the severity of CAL，the timing and role of coronary artery angiography，the natural history of CAL，and the progress of acute and long-term management of CAL in children with Kawasaki disease.

Key words: Kawasaki disease, coronary artery lesion, child

摘要：

川崎病冠状动脉病变已成为发达国家儿童获得性心脏病的首要病因。文章叙述川崎病患儿冠状动脉病变的诊断和评估以及冠状动脉病变的处理和随访，重点介绍超声心动图检测川崎病患儿冠状动脉的方法及冠状动脉病变严重程度的判断、冠状动脉造影的作用及时机、川崎病患儿冠状动脉病变的自然病史、川崎病冠状动脉病变的急性期和长期管理的进展。

关键词: 川崎病, 冠状动脉病变, 儿童