Abstract:

Acute kidney injury（AKI） is common in newborns，especially in preterm and low birth weight infants，with high mortality rate and poor prognosis. Renal replacement therapy is the effective treatment for AKI，including peritoneal dedialysis（PD），continuous renal replacement therapy（CRRT） and intermittent hemodialysis（HD）. CRRT was widely used in clinical practice in recent decades，but there was less experience in newborn. Indication，monitoring and care of CRRT in newborn were introduced in this paper.

Key words: continuous renal replacement therapy, newborn, acute kidney injury

摘要：

急性肾损伤（AKI）在新生儿中发生率高， 尤其是早产儿及低出生体重儿， 其病死率高、 预后差。肾替代治疗是AKI的有效治疗方法， 新生儿常用的肾替代治疗包括： 腹膜透析、 连续肾替代治疗及间断血液透析。其中，连续肾替代治疗已被广泛应用于临床， 但由于新生儿期应用较少， 该文对其应用的适应证、 监测、 护理等方面进行了介绍。

关键词: 连续肾替代治疗, 新生儿, 急性肾损伤