关键词: 主动脉缩窄, 儿童, 球囊, 支架

Abstract:

Objective　To evaluate the safety and curative effect of percutaneous interventional treatment for coarctation of aorta in children. Methods　Retrospectively analyze the data of 22 children who were treated with percutaneous interventional treatment for coarctation of aorta from February 2007 to May 2017 in our institute.The general clinical data，echocardiography，cardiac CT， angiography，interventional results， the procedure-related complications and follow-up results were assessed. Results　A total of 22 patients consisting of 13 boys and 9 girls underwent the procedure，with mean age of （8.7±5.7） years（ranging from 9 months to 17 years） and the mean body weight of （30.7±20） kg（ranging from 9.5 kg to 80.0 kg）. Totally 16 patients accepted balloon angioplasty and 6 patients accepted membrane-covered stent implantation. The catheter-measured narrowest aortic peak systolic gradient was successfully relieved in all the patients，decreasing from （52.7±25.0） mmHg to （9.7±11.4） mmHg immediately after percutaneous interventional treatment（t＝8.326，P＝0.000）. The diameter was increased from （5.3±1.9） mm to （10.0±3.8） mm immediately（t＝-6.996，P＝0.000）. During the procedure，two patients had limited aortic aneurysm，which disappeared after 3 to 6 months of follow-up without intervention. One needed surgery for left subclavian artery interrupted by stent； however，there were no deaths. The follow-up period was 3 months to 9 years. All patients hadn’t accepted interventional therapy or surgery again， and the stents had no deformation or restenosis. Conclusion　Percutaneous balloon angioplasty and stent implantation have reliable early and medium-term effect and high security for children’s aortic coarctation. Percutaneous balloon angioplasty also is a safe and acceptable option for restenosis after surgery.

Key words: coarctation of aorta, child, balloon, stent