中国实用儿科杂志

中国实用儿科杂志

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儿童风湿病国际相关诊治指南系列解读之二——幼年特发性关节炎分类标准解读

  

  1. 1.国家儿童健康与疾病临床医学研究中心（重庆） 重庆医科大学附属儿童医院风湿免疫科，重庆 400014；2.深圳市儿童医院风湿免疫科，深圳 518038
  • 出版日期:2020-04-06 发布日期:2020-04-20

Interpretation of international guidelines for diagnosis and treatment of rheumatism in children（Ⅱ）：Interpretation of the classification criteria of juvenile idiopathic arthritis

  1. *National Clinical Research Center for Child Health and Disorders（Chongqing），Children’s Hospital of Chongqing Medical University，Chongqing 400014，China
  • Online:2020-04-06 Published:2020-04-20

摘要： 幼年特发性关节炎（JIA）是一组儿童时期常见的慢性风湿性疾病，临床及转归都具有高度异质性，合理的分类标准对疾病的诊治及临床研究尤为重要。2001年国际风湿病联盟（ILAR）分类标准得到广泛认可及应用，随着对JIA临床特征及机制研究的不断深入，同时也为了使JIA患儿成年后更好接轨疾病命名，国际儿童风湿病国际试验组织（PRINTO）于2018年发表了新的JIA分类标准，其临床的合理性及可操作性尚需进一步验证。文章重点对两种JIA分类标准进行解析，旨在助力疾病诊断及鉴别。

关键词: 幼年特发性关节炎, 分类标准, 专家解读

Abstract: Juvenile idiopathic arthritis is a group of chronic rheumatoid disorders in children，which has a high heterogeneity in the clinical features and prognosis，so it is extremely important to establish an effective classification criteria for the disease treatment and clinical research. The 2001 International League of Associations for Rheumatology（ILAR） classification criteria for JIA has been accepted and used worldwide for decades. With the more intensive research in the clinical characters and pathogenesis，and for the better harmonization with adult definition，the Pediatric Rheumatology International Trials Organization（PRINTO） revised the criteria in 2018，which rationality and practicality needs further validation. We interpret the two classification criteria，aiming at provide assistance in JIA diagnosis and differentiation.

Key words: juvenile idiopathic arthritis, classification criteria, expert interpretation