关键词: 儿童, 青少年, 甲状腺癌, 指南, 诊疗

Abstract: Introduction to the key contents of domestic and foreign guidelines on thyroid cancer in children and adolescents            YIN De-tao, WANG Guan. Department of Thyroid Surgery, the First Affiliated Hospital of Zhengzhou University; Engineering Research Center of Multidisciplinary Diagnosis and Treatment of Thyroid Cancer of Henan Province; Key Medicine Laboratory of Thyroid Cancer of Henan Province,Zhengzhou 450052,China
Corresponding author：YIN De-tao, E-mail:detaoyin@zzu.edu.cn
Abstract    The clinical biological behavior of thyroid cancer in children and adolescents is more aggressive，and is more likely to have an extrathyroidal extension，regional lymphadenopathy，and pulmonary metastases compared with their adult counterparts，but the incidence of disease-specific mortality for pediatric and adolescent thyroid cancer(PATC) was significantly lower than that in adults. The diagnosis and treatment of PATC is not a "smaller version" of adults’. Previously，most of the evaluation，treatment and follow-up of PATC were based on adult guidelines，which led to some children receiving aggressive therapy unnecessarily—total thyroidectomy，neck dissection or radioactive iodine therapy. The formulation of domestic and foreign guidelines has optimized the diagnosis and management of pediatric and adolescent thyroid cancer for individualized treatment based on preoperative and postoperative staging and risk stratification，and the aim is to minimize the potential complications of treatment while maintaining low disease-specific mortality and to maximize the benefit of the child.

Key words: children, adolescents, thyroid cancer, guidelines, diagnosis and ,  , treatment