中国实用外科杂志

中国实用外科杂志

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131I在甲状腺癌术后复发诊治中应用

慕转转，林岩松   

  1. 中国医学科学院 北京协和医学院 北京协和医院核医学科，疑难重症及罕见病国家重点实验室；核医学分子靶向诊疗北京市重点实验室，北京 100730
  • 出版日期:2021-08-01 发布日期:2021-08-10

  • Online:2021-08-01 Published:2021-08-10

摘要： 分化型甲状腺癌（DTC）总体预后良好，死亡风险低，其管理重点在于防治肿瘤复发及对复发疾病的妥善处理。131I作为DTC诊治的重要辅助手段，在复发疾病中仍然发挥着独特的诊治作用，主要包括复发灶的定位、摄碘性判断以及针对不可手术切除的摄碘性复发疾病的治疗。准确把握131I在DTC术后复发中的应用指征，将有助于提高综合治疗效果，改善病人预后及生活质量。

关键词: 甲状腺癌, 放射性碘同位素, 肿瘤复发

Abstract: Role of 131I in the diagnosis and treatment of postoperative recurrence of thyroid cancer        MU Zhuan-zhuan，LIN Yan-song. Department of Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College (PUMC) Hospital, Chinese Academy of Medical Sciences & PUMC；Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine，Beijing 100730，China
Corresponding author: LIN Yan-song，E-mail: linys@pumch.cn
Abstract    Differentiated thyroid cancer (DTC) generally has a good prognosis and a low risk of death. Thus, the management mainly focuses on the prevention and proper treatment of recurrent diseases. As an important auxiliary method for DTC diagnosis and treatment, 131I plays a unique role in the recurrent diseases, including the location of recurrent lesions, the judgment of radioiodine (RAI) avidity, and the treatment of unresectable RAI-avid recurrent diseases. Accurate application of 131I in postoperative recurrence of DTC will help to enhance the comprehensive curative effect and improve patients’ prognosis and quality of life.

Key words: thyroid cancer, radioiodine, tumor recurrence