关键词: 甲状腺髓样癌, 术后复发, 治疗原则

Abstract: Principles of management for postoperative recurrence of medullary thyroid carcinoma        WANG Yu, QU Ning, WEI Wen-jun, et al. Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Corresponding author: WANG Yu, E-mail: neck130@hotmail.com
Abstract    Medullary thyroid carcinoma (MTC) has a tendency to develop local recurrence, regional lymph node invasion, and distant metastasis to lungs and bones after initial treatment, and the prognosis is relatively poor. There are still controversies and divergences on some issues in clinical practice, such as postoperative follow-up evaluation plans and therapeutic principles for recurrent patients. The principles of management for recurrent MTC based on the consensus of domestic and foreign guidelines, and the relevant research results of author’s center, surgical treatment is the main treatment for patients with local recurrence of clear lesions, while the individualized systemic treatment on gene targets is recommended to patients with unresectable lesions or distant metastasis.

Key words: medullary thyroid carcinoma, postoperative recurrence, therapeutic principle