中国实用外科杂志

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胰腺坏死组织感染的影像学特征、微创介入方式及时机

高    堃,童智慧李维勤   

  1. 南京医科大学金陵临床医学院  中国人民解放军东部战区总医院普通外科,江苏南京210002
  • 出版日期:2019-06-01 发布日期:2019-06-12

  • Online:2019-06-01 Published:2019-06-12

摘要:

近年来,人们对胰腺坏死组织感染(IPN)的认识日趋深入,“气泡征”作为诊断IPN的金标准、干预时机应当尽量延迟到4周以后以及将阶梯引流模式作为IPN治疗的首选策略已被广泛接受。但实际的临床实践中仍然会遇到很多新的问题:“气泡征”阴性的IPN病人仍缺乏可靠的诊断标准;早期感染的包裹性坏死是否要延迟至4周以后干预尚未达成共识;以内镜为核心的阶梯引流策略与微创外科相比孰优孰劣,不同研究结论尚不统一;开放手术在IPN治疗中的地位以及手术时机的把握依旧充满争论等。

关键词: 急性胰腺炎, 胰腺坏死组织感染, 阶梯式引流

Abstract:

Imaging features, when and how to perform minimally invasive intervention in infected pancreatic necrosis patients        GAO Kun,TONG Zhi-hui,LI Wei-qin. Department of General Surgery,Jinling Hospital,Jinling Clinical Medical College of Nanjing Medical University,General Hospital of Eastern Military Command of PLA, Nanjing210002, China
Correspondingauthor:LI Wei-qin,E-mail:liweiqindr@vip.163.com
Abstract    Recently,with the further understanding of infected pancreatic necrosis (IPN),pancreatologists have reached consensuses on that the presence of gas on CT imaging could be the golden standard diagnosis for IPN,the intervention timing for IPN should be delayed to four weeks later,and the step-up approach acts as the first standard treatment strategy for IPN.Whereas in clinical practice,there are substantial new challenges awaiting our solutions,for instance,the lack of accurate and specific diagnostic criteria for IPN without typical gas sign on CT imaging,whether the intervention of wall-off necrosis(WON)which got infected prematurely should be delayed to four weeks later?What’s more,whether the endoscopy centered step-up approach is superior to the surgical step-up approach?Is it time to abandon open surgery in IPN management?If not,when should we switch to open necrosectomy?All of these questions are still full of controversies.

Key words: acute pancreatitis, infected pancreatic necrosis, step-up approach