中国实用外科杂志

• 普通外科进展 • 上一篇    下一篇

早期胃癌治疗的共识与问题

李子禹王胤奎,陕    飞,季加孚   

  1. 北京大学肿瘤医院暨北京市肿瘤防治研究所胃肠肿瘤中心  恶性肿瘤发病机制及转化研究教育部重点实验室,北京 100142
  • 出版日期:2018-02-01 发布日期:2018-02-24

  • Online:2018-02-01 Published:2018-02-24

摘要:

目前,早期胃癌的治疗共识与争议并存。一方面,在符合适应证前提下,内镜治疗在安全性和预后方面均可以接受,且比手术治疗更加微创,是符合内镜治疗指征病人的首选方式;与进展期胃癌相比,早期胃癌的手术治疗在原发灶切除及淋巴结清扫范围方面有不同的要求;有经验及条件的中心可考虑选用腹腔镜或机器人等微创手术方式,这些现已达成业内共识。另一方面,如何提高临床分期的准确性,如何为符合内镜治疗扩大适应证的人群选择合理的治疗方式,如何处置内镜治疗切缘阳性的病人,怎样进行前哨淋巴结活检的探索以及保留功能手术的研究,如何应对我国现状下的早期胃癌治疗等仍存在争议。总体而言,早期胃癌的治疗模式呈现多元化,向精准靠近,内镜与微创手术的结合可能是今后早期胃癌治疗发展的热点。

关键词: 早期胃癌, 胃切除术, 内镜治疗

Abstract:

Consensus and controversy in the treatment of early gastric cancer        LI Zi-yu, WANG Yin-kui, SHAN Fei,et al. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education),Gastrointestinal Cancer Center,Peking University Cancer Hospital & Institute,Beijing 100142,China
Corresponding author:LI Zi-yu,E-mail:ligregory@outlook.com
Abstract    Nowadays both the consensus and controversy exist in the treatment of early gastric cancer. On one hand , consensus has been reached in some fields. For example, endoscopic therapy is safe and effective for the early gastric cancer patients meeting the indications, which should be the initial choice with the advantage of minimally invasive. The resection range of stomach and lymph nodes for early gastric cancer is different from that of advanced gastric cancer. Laparoscopic surgery or robotic surgery can be applied in experienced center. On the other hand, some controversies are still unresolved, such as how to improve the accuracy of clinical stage, how to choose the appropriate treatment for expanded indication lesion, what to do if the patient had a positive margin after endoscopic therapy, how to investigate the application of sentinel node mapping and function-preserving gastrectomy, and so on. In general, treatment mode of early gastric cancer is becoming diversified and precision. Perhaps, the combination of laparoscopic surgery and endoscopic therapy will be the hot spot of early gastric cancer in the future.

Key words: early gastric cancer, gastrectomy, endoscopic therapy