关键词: 胰十二指肠切除术, 无接触分离技术, 肝脏转移

Abstract:

Application and significance of no-touch isolation technique in pancreaticoduodenectomy        LOU Wen-hui，FANG Yuan. Department of General Surgery，Zhongshan Hospital of Fudan University，Shanghai 200032，China
Corresponding author: LOU Wen-hui, E-mail: Lou.wenhui@
zs-hospital.sh.cn
Abstract    The rate of recurrence including liver metastasis of pancreatic cancer is considerably high even after radical pancreaticoduodenectomy. The intraoperative grasping and squeezing of the pancreas may increase the risk of cancer cells spreading via portal vein leading to liver metastasis，which may be prevented by the no-touch isolation technique. While no-touch isolation techniques are feasible and safe theoretically，there have been no prospective randomized controlled studies and prognostic data to confirm their advantages. Moreover，for the advanced pancreatic head tumor，this technique should be used very cautiously. It is therefore that we need implement more study to investigate the clinical advantages of no-touch isolation techniques in the pancreaticoduodenectomy.

Key words: pancreaticoduodenectomy, no-touch isolation technique, liver metastasis