关键词: 胰腺癌, 胰十二指肠切除术, 淋巴结清扫

Abstract:

The controversies and consensus of lymphadenectomy extent in pancreaticoduodenectomy for pancreatic carcinoma        YANG Yin-mo. Department of Surgery，Beijing University First Hospital，Beijing 100034，China
Abstract    The optimal lymphadenectomy during pancreaticoduodenectomy for pancreatic carcinoma remains controversial. In order to investigate the survival benefit of standard and extended lymphadenectomies during pancreaticoduodenectomy，the retrospective studies，prospective randomized and nonrandomized controlled trials，and consensus statement were reviewed. Based on the results from these literatures，it can be concluded that pancreaticoduodehadenectomy demands an adequate minimum total number of lymph node，and extended lymphadenectomy is not recommended. In addition，standard lymphadenectomy for pancreaticoduodenectomy should strive to resect the following LN stations：6，8a-p，12a-b-c，13，14a-b，16b1，17. Moreover，metastasis to 16b1 significantly worsens prognosis. Their removal and frozen examination，before proceeding with resection，may contraindicate resection. 

Key words: pancreatic cancer, pancreaticoduodenectomy, lymphadenectomy