中国实用外科杂志
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虞文魁,石佳靓,朱维铭
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创伤、手术应激、感染等原因所致的全身炎性反应综合征可引起外科病人异常的容量需求。液体复苏的目的是在恢复有效循环血量的同时改善组织和器官功能。人血白蛋白是外科病人复苏常用的胶体,但其使用一直存在争议。大量研究表明使用人血白蛋白进行复苏是安全的。与使用晶体复苏相比,白蛋白复苏更有利于稳定病人血流动力学指标,但两种策略对病人预后的影响差异并无统计学意义。外科病人的液体复苏量及种类须根据具体情况进行选择,需要高质量的随机对照研究指导临床治疗。
关键词: 白蛋白, 复苏, 围手术期, 液体复苏
Abstract:
Controversies and consensus on albumin in perioperative fluid resuscitation YU Wen-kui,SHI Jia-liang,ZHU Wei-ming. Department of General Surgery,Nanjing General Hospital of Nanjing Military Command of PLA,Nanjing 210002,China Corresponding author:ZHU Wei-ming,E-mail:juwiming@126.com Abstract Resuscitation is required in patients with systemic inflammatory response syndrome from trauma,surgical stress and sepsis. Fluid therapy is targeted primarily at restoring intravascular volume and improving organs function. Human albumin is a natural colloid used as volume expander in resuscitation,but its use in resuscitation remains hotly debated. Recent studies found no difference in outcomes in patients receiving albumin or saline despite some evidence that resuscitation with albumin is safe and result in greater intravascular volume. Best practice for fluid resuscitation in surgical patients must consider the types,timing,and volume of fluids,which still demands clinical study of high quality.
Key words: albumin, resuscitation, perioperative period, fluid resuscitation
虞文魁,石佳靓,朱维铭. 外科病人液体复苏应用白蛋白争议与共识[J]. 中国实用外科杂志, DOI: 10.7504/CJPS.ISSN1005-2208.2015.02.06.
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https://www.zgsyz.com/zgsywk/CN/Y2015/V35/I02/142