中国实用外科杂志

中国实用外科杂志 ›› 2011, Vol. 31 ›› Issue (12): 1083-1085.

• 专题笔谈 • 上一篇    下一篇

溶栓药物在肢体缺血治疗中的地位及评价

黄晓钟，张纪蔚   

  1. 上海交通大学医学院附属仁济医院血管外科，上海 200127
  • 出版日期:2011-12-01 发布日期:2011-11-28

  • Online:2011-12-01 Published:2011-11-28

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摘要：

肢体动脉血栓在周围血管疾病中占很大比例，并以其高发病率、致残率和病死率严重危害人类健康，溶栓疗法是目前最重要的治疗方法之一。近年来溶栓药物的使用与研究有了很大的进展，主要集中在两大方面：（1）对传统溶栓药物的进一步深刻了解，并对其精确使用；（2）新型溶栓药物的研究成功，如通过生物技术改造的新型纤溶酶原激活剂、新型经改造的天然来源溶栓药，给溶栓治疗带来新的契机。

关键词: 溶栓药物, 动脉血栓病, 溶栓治疗

Abstract:

The status and value of thrombolysis drugs in the treatment of limb ischemia        HUANG Xiao-zhong, ZHANG Ji-wei. Department of Vascular Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai200127, China
Corresponding author: ZHANG Ji-wei, E-mail：zhangjiwei001@sina.com
Abstract    Artery thromboembolism of limbs accouts for a large proportion in peripheral vascular diseases with high morbidity and mortality. It could harm the preservation of limbs and human health. Fibrinolytic therapy is one of the most important ways of the treatment. In recent years thrombolysis drug use and research have made a lot of progress. Concentrated in two ways: (1) Deep and further understanding of the traditional thrombolysis drugs, achieveing the precise use. (2) New thrombolysis drugs success to fibrinolytic therapy bring new opportunities.

Key words: thrombolysis drugs, artery thromboembolism, fibrinolytic therapy