中国实用外科杂志

中国实用外科杂志 ›› 2009, Vol. 29 ›› Issue (04): 327-330.

• 论著 • 上一篇    下一篇

恶性胃肠道间质瘤CT影像特点研究

孙雪峰1，张晓鹏1,唐 磊1,孙应实1,崔 涌1,曹 崑1,周 毅1,汪 宁1,李 洁1,单 军1   

  1. 1北京大学临床肿瘤学院，北京肿瘤医院暨北京市肿瘤防治研究所医学影像科,北京100036；2首都儿科研究所附属儿童医院，北京100020
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-04-03 发布日期:2009-04-03

  • Received:1900-01-01 Revised:1900-01-01 Online:2009-04-03 Published:2009-04-03

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摘要：

目的 从良恶性胃肠道间质瘤（GISTs）的CT影像学鉴别的角度出发，重点探讨恶性GISTs的影像学表现。方法 回顾性分析北京肿瘤医院2004-01-01至2006-10-31期间46例GISTs原发灶的CT影像表现，并行统计学分析，判断其对良恶性诊断的价值。结果 46例GISTs中，良性14例，恶性32例。两者在肿瘤大小、肿瘤边界情况、强化方式、并发溃疡、瘤周及瘤体内簇状或线状排列血管影显示等方面的差异具有统计学意义（P <0.05）。GISTs的生长方式、强化程度及有无钙化在良恶性鉴别上的差异无统计学意义（P >0.05）。结论 良性与恶性GISTs在CT影像表现上存在差异，恶性GISTs多表现为边缘不规则的较大肿块、不均匀强化、并发溃疡、瘤周及瘤体内簇状或线状排列的扩张血管影。在判断GISTs良恶性时要综合多方面的影像学表现进行分析。

关键词: 胃肠道间质瘤, 计算机体层成像

Abstract:

Study of CT imaging in diagnosis of malignant gastrointestinal stromal tumors SUN Xue-feng*,ZHANG Xiao-peng,TANG Lei, et al. *Department of Radiology, Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100036, China Corresponding author: Zhang Xiao-peng, E-mail: zxp@bjcancer.org Abstract Objective To investigate the CT imaging features of malignant gastrointestinal stromal tumors (GISTs). Methods The morphologic characteristics of tumor were evaluated according to tumor size, shape, homogeneity, density compared with liver, contrast enhancement, presence of calcifications, ulcerations and the anatomical relationship to the intestinal wall, and the infiltration of adjacent visceral organs. Results Of the 46 patients with GISTs, 14 cases were classified as benign tumors, 32 cases as malignant tumors.There were differences in size,margin, enhancement pattern between benign and malignant tumors. Presence of ulcers or small vessels in /around the tumor arranged in clumps or in line was more frequently observed in primary malignant GISTs (P <0.05). No statistical differences of enhancement degree, growth pattern and presence of calcifications were observed between benign and malignant GISTs. Conclusion Malignant GISTs are typically large, with irregular margin and heterogeneous enhancement pattern. Presence of ulcers, and small vessels in/around the tumor which arranged in clumps or in line are more frequently observed in primary malignant GISTs. There are no differences in enhancement degree, growth pattern, and presence of the calcifications between benign and malignant GISTs.

Key words: gastrointestinal stromal tumor, computed tomography