中国实用外科杂志 ›› 2012, Vol. 32 ›› Issue (10): 793-795.
• 院士论坛 • 下一篇
吴孟超
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摘要:
肝切除术是治疗原发性肝细胞癌的主要手段,但术后复发极大影响了肝癌切除术后的远期疗效。影响肝癌术后复发的因素主要包括肿瘤及病人本身、外科手术操作、术后干预措施等方面。一方面,可以通过在肝癌人群中早诊断、早手术以及提高整个外科医生队伍的肝切除术水平来降低整个手术人群总体术后复发率;另一方面,还可以通过深入研究一些新的药物或辅助措施来干预术后复发的发生发展。转化医学的研究模式和多学科的交叉协作最终会使肝癌术后复发的这一课题得到突破性进展。
关键词: 肝癌肝切除术, 术后复发, 转化医学, 多学科交叉协作, 经肝动脉化疗栓塞, 放射治疗, 分子靶向治疗
Abstract:
Reducing liver cancer recurrence rate WU Meng-chao. Eastern Hepatobiliary Surgery Hospital,the Second Miliarty Medical University, Shanghai 200438, China Abstract Hepatectomy is one of the main curative treatment for primary hepatocellular carcinoma (HCC), but postoperative recurrence greatly hinders its long-term outcomes. The factors influencing recurrence after hepatectomy of HCC include patients and their existing tumors, surgical procedures and intervening measures after operation and so on. On one hand, it is useful for decreasing the overall recurrence rate after hepatectomy of HCC to diagnose and operate as early as possible all over the mainland, and to improve the overall surgical levels of hepatectomy. On the other hand, developing new drugs or intervention measures are really to be expected to prevent recurrence of HCC after hepatectomy. Significant progress would be finally made in the field through translational research models and interdisciplinary collaboration.
Key words: liver cancer hepatectomy, postoperative recurrence, translational medicine, multidisciplinary collaboration, TACE, radio therapy, molecular targeted therapy
吴孟超. 关于降低肝癌术后复发率之我见[J]. 中国实用外科杂志, 2012, 32(10): 793-795.
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