中国实用外科杂志

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国内外有关肝内胆管癌分型分期解读

李秉璐,吴    昕   

  1. 中国医学科学院 北京协和医院基本外科,北京100730
  • 出版日期:2020-06-01 发布日期:2020-06-24

  • Online:2020-06-01 Published:2020-06-24

摘要: 肝内胆管癌(ICC)的发病率近年来逐渐提高,日益引起人们的重视。世界卫生组织、美国癌症联合委员会以及美国国家综合癌症网络等都先后发表了针对ICC的分型分期研究结果。这些分型分期方法尚不统一,互有补充,各有优势。分型主要基于肿瘤的生长模式和微观特征,从起源和生物学行为上对肿瘤进行分类,并为将来的靶向治疗提供了可能的方向。分期主要基于不同发展阶段肿瘤的预后差异,以影像和病理信息来评估肿瘤、判断预后,并指导不同期别肿瘤的合理治疗。充分了解各种分型分期系统,能够帮助人们加深对于ICC的认识,提高诊治疾病的能力,并明确未来的研究方向。

关键词: 肝内胆管癌, 分型, 分期

Abstract: Interpretation of the typing and staging systems of intrahepatic cholangiocarcinoma at home and abroad                  LI Bing-lu, WU Xin. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Corresponding author:LI Bing-lu,E-mail:libinglu@pumch.cn
Abstract    The incidence of intrahepatic cholangiocarcinoma(ICC)has been increasing in recent years,which has been paid more and more attention by people. World Health Organization,American Joint Committee on Cancer,National Comprehensive Cancer Network,and other institutions have published several different results of the typing and staging systems of ICC. Those systems are not uniform,but complementary and each has its own advantages. Typing systems are based on the growth pattern and microscopic features. They classify tumors by their origin and biological behavior,and provide possible directions for the future targeted therapy. Staging systems are based on the different prognosis of tumors with different phases. They evaluate tumors by imaging and pathological information,and suggest suitable treatment for tumors with different stages. A full understanding of the typing and staging systems is helpful in recognizing ICC,improving the ability of diagnosis and treatment,and clarifying the future research direction.

Key words: intrahepatic cholangiocarcinoma, typing, staging