关键词: 肝细胞癌, 手术切缘, 指南

Abstract:

Interpretation of liver resection margin from the guidelines of China and abroad about liver cancer                      DAI Chao-liu，JIA Chang-jun. Department of Hepatobiliary and Splenic Surgery，Shengjing Hospital of China Medical University，Shenyang 110004，China
Corresponding author：DAI Chao-liu，E-mail：daicl@
sj-hospital.org
Abstract    The surgical resection margin is an important prognostic factor of postoperative recurrence and survival in hepatectomy for patients with hepatocellular carcinoma (HCC). Negative surgical resection margin (R0) can reduce the postoperative recurrence rate and improve the prognosis of patients with HCC. But the effect of resection margin width on recurrence-free survival and long-term survival is still controversial. Under the premise of sufficient future liver remnant，the width of resection margin ≥ 1 cm should be recommended in most conditions. But recurrence after primary resection is multifactorial，R0 resection is just one of the problems in the treatment of HCC. Optimization of individual multidisciplinary therapy is an important way to improve the overall efficacy of HCC.

Key words: hepatocellular carcinoma, resection margin, guideline