中国实用外科杂志

• 专题笔谈 • 上一篇    下一篇

颈动脉狭窄规范化治疗争议与共识

唐    骁,郭大乔符伟国   

  1. 复旦大学附属中山医院血管外科  复旦大学血管外科研究所,上海200032
  • 出版日期:2017-12-01 发布日期:2017-11-30

  • Online:2017-12-01 Published:2017-11-30

摘要:

颈动脉狭窄是缺血性脑梗死公认的主要危险因素之一。在20世纪80年代末和90年代,多项设计严密的随机对照临床试验证实了颈动脉内膜切除术的重要价值。虽然这些里程碑式的临床研究帮助确立了目前的治疗指南,但颈动脉血运重建的技术方法仍然存在较多争议。目前的药物治疗显著降低了无症状颈动脉狭窄病人的脑梗死风险,腔内治疗或手术治疗的适应证选择仍是临床需要重点考虑的问题。

关键词: 颈动脉狭窄, 规范化治疗

Abstract:

Evidence based treatment for carotid artery stenosis: Controversy and consensus        TANG Xiao, GUO Da-qiao,FU Wei-guo. Department of Vascular Surgery, Institute of Vascular Surgery, Zhongshan Hospital, Fudan University,Shanghai 200032,China
Corresponding author:FU Wei-guo,E-mail:fu.weiguo@
zs-hospital.sh.cn
Abstract    Carotid artery stenosis is a well-recognized risk factor for ischemic stroke. In the late 1980s and in the 1990s, well-designed randomized trials established a definite advantage for carotid endarterectomy. Although those landmark trials have helped to establish the current guidelines, there still remains a great deal of controversy regarding the technical approach to carotid revascularization.In particular, current medical treatment has drastically decreased the risk of stroke in patients with asymptomatic carotid stenosis. Selecting patients amenable to endovascular or surgical treatment still needs to be resolved.

Key words: carotid artery stenosis, evidence based treatment