关键词: 结直肠癌, 肝转移, 危险因素, 预后因素

Abstract:

Risk and prognostic factors of colorectal liver metastases          LIANG Li, LIU Tian-shu. Department of Medical Oncology，Zhongshan Hospital, Fudan University，Shanghai 200032, China
Corresponding author: LIU Tian-shu, E-mail: liu.tianshu@
zs-hospital.sh.cn
Abstract    Liver is the most common metastasis site of colorectal cancer, and the prognosis of colorectal liver metastases (CRLM)is poor. CRLM are divided into synchronous metastasis and metachronous metastasis. Single factor and multiple factor regression analyses show that the risk factors of CRLM include the depth of invasion, lymph node metastasis, tumor node, differentiation degree, tumor antigen and carbohydrate antigen. The factors influencing the prognosis of CRLM include the size and quantity of liver metastases, primary resection, surgical resection of liver metastases, systemic drug therapy and so on. Therefore, the surgical resection of liver metastases as well as drug therapy to get the opportunity of resection can maximize the survival of patients with CRLM. For a combination of a number of factors, the scoring system can better predict the prognosis of CRLM.

Key words: colorectal cancer, liver metastasis, risk factor, prognostic factor