中国实用外科杂志

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十二指肠间质瘤诊治策略

所    剑,李    伟,王大广   

  1. 吉林大学第一医院胃结直肠肛门外科,吉林长春130021
  • 出版日期:2015-04-01 发布日期:2015-03-31

  • Online:2015-04-01 Published:2015-03-31

摘要:

胃肠间质瘤是来源于胃肠道未定向分化的的间质细胞肿瘤,可以发生于消化道的各个部位,十二指肠间质瘤的发生率较低。十二指肠间质瘤多见于中老年人,临床表现不典型,早期诊断困难,需要结合腹部CT、内镜及超声内镜等辅助检查协助诊断,但是最终依靠组织病理学以及免疫组织化学检测结果确定。手术治疗是十二指肠间质瘤的有效治疗方法,包括胰十二指肠切除术、十二指肠局部切除、十二指肠节段切除术、胃大部切除术等,需要根据肿瘤的大小、部位、与周围组织器官的关系以及基因检测结果制定个体化的、规范的手术及辅助治疗方案。

关键词: 十二指肠间质瘤, 胃肠间质瘤

Abstract:

Diagnosis and therapeutic strategies of duodenal stromal tumor        SUO Jian, LI Wei, WANG Da-guang. Department of Gastric and Colorectal Surgery, the First Hospital of Jilin University, Changchun 130021, China
Corresponding author: SUO Jian, E-mail: suojian0066@126.com
Abstract    Gastrointestinal stromal tumors (GIST) is the most common mesenchymal tumors of the gastrointestinal tract and occur in any part of the gastrointestinal tract. But the incidence of duodenal stromal tumors is very low. They usually occur in the middle aged and elderly people and clinical symptoms are unrepresentative. The early diagnosis is difficult and should combine abdominal CT, endoscopy and endoscopic ultrasonography, but depends on histopathology and immunohistochemistry finally. Surgical operation is the best effective treament of duodenal stromal tumors, including pancreaticoduodenectomy, subtotal gastrectomy, segmental duodenectomy and simple tumor resection, etc. The individualized, normative operation and adjuvant therapy of duodenal stromal tumors are according to the size, location, adjacent organs of tumors and their genetic test results.

Key words: duodenal stromal tumor, gastrointestinal stromal tumor