中国实用外科杂志
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周文涛1,李初实2,匡天涛1,楼文晖1,王单松1
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目的 探讨胰高血糖素瘤的临床特征及诊治要点。方法 回顾性分析复旦大学附属中山医院2014-07-01收治的1例胰高血糖素瘤病人资料,并结合文献复习。结果 该病人有典型的溶解游走性坏死性红斑、糖尿病、贫血及消瘦等胰高血糖素瘤综合征表现,曾多次误诊为皮炎。腹部CT示胰体尾占位性病变。经胰体尾联合脾脏切除术治疗后,血糖恢复正常,症状体征明显改善。结论 胰高血糖素瘤临床表现复杂,易误诊,影像学检查对诊断有一定帮助,手术切除是其有效的治疗方法。
关键词: 胰高血糖素瘤综合征, 溶解坏死性游走性红斑, 糖尿病
Abstract:
Glucagonoma syndrome:A report of one case and review of literature ZHOU Wen-tao*,LI Chu-shi,KUANG Tian-tao,et al. *Department of General Surgery , Zhongshan Hospital of Fudan University, Shanghai 200032, China Corresponding author:LOU Wen-hui,E-mail:lou.wenhui@zs-hospital.sh.cn Abstract Objective To investigate the clinical features,diagnosis and treatments of glucagonoma. Methods The clinical data of one patient with glucagnoma admitted in Zhongshan Hospital of Fudan University was analyzed retrospectively. Results The patient had been misdiagnosed as dermatitis for many times. Although the patient got the typical symptoms of glucagonoma syndrome such as necrolytic migratory erythema,diabetes mellitus,anemia,weight loss and so on. Abdominal CT scan showed a tumor mass in pancreatic body and tail. After surgical removal of the tumor,the patient’s glucose level and systemic features resolved. Conclusion Glucagonoma is very easy to get misdiagnosis because of its multiple clinical manifestations. Imaging examination is helpful for the diagnosis and surgical resection is still an effective method.
Key words: glucagonoma syndrome, necrolytic migratory erythema, diabetes mellitus
周文涛1,李初实2,匡天涛1,楼文晖1,王单松1. 胰高血糖素瘤综合征1例报告并文献复习[J]. 中国实用外科杂志, DOI: 10.7504/CJPS.ISSN1005-2208.2015.03.21.
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