中国实用外科杂志

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第6版日本《胃癌治疗指南》外科治疗部分更新要点解读

高梓茗,朱    志,王振宁,李    凯,徐惠绵   

  1. 中国医科大学附属第一医院胃肠肿瘤外科,辽宁沈阳 110001
  • 出版日期:2022-01-01

  • Online:2022-01-01

摘要: 2021年7月,日本胃癌学会发布了第6版《胃癌治疗指南》。较第5版更新了9个外科治疗方向的17个相关临床问题。对胃癌微创手术适应证的推荐仍较为谨慎,仅对cⅠ期强推荐腹腔镜下胃远端切除术,对腹腔镜下近端或全胃切除术及机器人手术均为弱推荐。早期胃体癌弱推荐保留幽门的胃切除术,胃上部癌则弱推荐近端胃切除。弱推荐对cT3-T4者行大网膜切除术;对于侵及大弯侧胃上部癌,弱推荐脾切除或脾门淋巴结清扫,但未侵犯胃大弯则强烈不推荐。食管胃结合部癌纵隔淋巴结清扫范围取决于食管浸润长度,即以2 cm或4 cm为界进行评估。因食管胃结合部癌的No.16a2b1的清扫尚存争议,未给出明确推荐。

关键词: 胃癌, 外科治疗, 指南

Abstract: Interpretation of surgical update in Japanese Gastric Cancer Treatment Guidelines (the 6th edition)        GAO Zi-ming, ZHU Zhi, WANG Zhen-ning, et al. Department of Surgical Oncology, the First Hospital of China Medical University, Shenyang 110001, China.
Corresponding author: XU Hui-mian, E-mail: xuhuimian@126.com
Abstract    In July 2021, Japanese Gastric Cancer Association (JGCA) published the Version 6th of Japanese Gastric Cancer Treatment Guidelines. Compared with previous version, surgical update included 9 clinical subject, involving 17 related clinical questions. The Version 6th guidelines were still cautious in indications of minimally invasive gastrectomy. Only laparoscopy-assisted distal gastrectomy was strongly recommended for cⅠstage, laparoscopy-assisted proximal/total gastrectomy or robotic surgery was weakly recommended. The guidelines weakly recommended pylorus-preserving gastrectomy for early gastric corpus cancer and proximal gastrectomy for proximal gastric cancer. Omentectomy was weakly recommend for cT3-T4 stage. Splenectomy or hilar lymph node dissection was weakly recommended for lesion invading greater curvature, but was strongly not recommended if not invading. Dissection extent of mediastinal lymph node for cT2+ stage esophagogastric junction cancer mainly depended on esophageal invasion length, which was based on the boundary of 2cm and 4cm. However, for No. 16a2b1, the guidelines couldn’t provide explicit recommendation.

Key words: gastric cancer, surgical therapy, guideline