中国实用外科杂志

中国实用外科杂志

• 专题笔谈 • 上一篇    下一篇

进展期胰腺癌术中放疗效果评价

王成锋   

  1. 中国国家癌症中心  中国医学科学院  北京协和医学院肿瘤医院胰胃外科，北京 100021
  • 出版日期:2017-07-01 发布日期:2017-06-30

  • Online:2017-07-01 Published:2017-06-30

摘要：

进展期胰腺癌临床治疗效果较差，且治疗手段多存在争议。术中放疗具有准确的靶区定位、肯定的周围器官保护、良好的局部控制、较少的并发症以及可延长生存期、改善生活质量的优势；而且术中组织细胞学检查获取方便、安全；可同时解除胆道梗阻、解除或预防消化道梗阻，是进展期胰腺癌有效的治疗手段。以术中放疗为基础的多学科综合治疗，对进展期胰腺癌是一种疗效好、操作方便、安全的治疗手段，但缺点是设备昂贵、环境要求高。

关键词: 胰腺癌, 进展期, 术中放疗, 疗效评估

Abstract:

Effect assessment of intraoperative radiotherapy for advanced pancreatic cancer        WANG Cheng-feng. Department of Pancreatic and Gastric Surgery, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Chinese National Cancer Center, Beijing 100021，China
Abstract    The treatment effect of advanced pancreatic cancer is poor, and the treatment methods are more controversial. Intraoperative radiotherapy（IORT） has accurate target positioning，around certain viscera protection，good local control and less complications，which can prolong survival and improve quality of life. Intraoperative tissue cytology determination is convenient and safe. IORT can relieve biliary obstruction, remove or prevent the digestive tract obstruction at the same time，which is an effective treatment of advanced pancreatic cancer. IORT based comprehensive treatment, multidisciplinary, multiple therapy for advanced pancreatic cancer is a kind of good curative effect，convenient operation and safe treatment. But the equipment is expensive and high environmental requirements are the short board.

Key words: pancreatic cancer, advanced stage, intraoperative radiotherapy, curative effect evaluation