关键词: 胰腺癌, 分类, 定义, 新辅助治疗, 多学科综合治疗协作组

Abstract:

The mode of MDT gives rise to the concept modification about surgical treatments of pancreatic carcinoma                      YANG Yin-mo. Department of Surgery，Peking University First Hospital，Beijing 100034，China
Abstract    Pancreatic carcinoma has the poorest prognosis in all the digestive cancers，and the management is still challenging. Nowadays the treatment strategy of pancreatic carcinoma has been changed from “surgery first” into the mode of multi-disciplinary team(MDT). Preoperative therapy is recommended for patients with borderline resectable pancreatic carcinoma so as to increase the R0 rates and improve the prognosis. However，there continues to be a blurring about the definitions of borderline resectability，which are all too often institution and operator dependent. Randomized clinical trials are needed to further evaluate the clinical outcome of preoperative therapy. Both the resectable and borderline resectable tumors could be defined as potentially curable pancreatic cancer. The definition change reflects the conversion from the mode of morphology and surgery to biology and oncology.

Key words: pancreatic carcinoma, classification, definitio, neoadjurant therapy, multi-disciplinary team