Abstract: Abstract：CAD/CAM technology has been applied to dentistry for over 20 years. Its rapid development and improvement have broadened the scope for prosthetic implant treatment and brought profound changes to it. Traditionally， mucosa-supported f dentures for patients with edentulous jaws cannot acquire reliable retention and restore efficient mastication，which is due to poor alveolar bone conditions. However，implant-supported fixed dentures radically overcome the problem of retention and stabilization，but implant-supported long fixed bridges cannot be fabricated and placed with ease. Prostheses made by computer-aided design and computer-assisted manufacturing （CAD/CAM） possess fit accuracy，ideal mechanical properties and biocompatibility. The present article introduced the CAD/CAM technology on its beginning，development as well as its application （constitution，prosthetic process and precautions for use） by describing a case of a patient with edentulous jaws and severely atrophic alveolar bone who had received the implant supported fixed restoration by CAD/CAM in order to provide indications for clinical applications

摘要： 计算机辅助设计和制作系统（CAD/CAM）应用于牙科学领域已有20余年历史，其快速发展和不断完善为口腔种植修复治疗提供越来越广泛的服务。无牙颌患者因颌骨条件较差，传统的黏膜支持式义齿通常存在固位不佳、咀嚼功能恢复不良的问题。种植体支持的固定义齿彻底改善了无牙颌患者的固位和稳定，但种植固定长桥的制作及就位困难。利用CAD/CAM制作的无牙颌修复体具有精确的边缘密合性、良好的机械学性能及生物相容性，本文介绍CAD/CAM技术发生、发展、制作过程及临床应用注意事项，并通过运用CAD/CAM技术完成1例颌骨重度萎缩无牙颌患者的种植修复。