Abstract:  Abstract：Synovial sarcoma accounts for about 6%～9% of soft tissue sarcomas， most commonly affecting the extremity of adults. Synovial sarcomas often develop in para-articular regions of the extremity， and they almost never arise within the joint. Synovial sarcomas have always been considered high-grade and carry a particularly different molecular mechanism and its pathological diagnosis remains distinct. Given the rapid growth and infiltrative nature of the disease， local and systemic control is challenging and tough to surgeons， radio-oncologists and chemo-therapists. Head and neck synovial sarcomas are rare entities in adults， accounting for only about 3%～5% of all synovial sarcomas. Therefore， the medical literature on synovial sarcomas of the head and neck is so far limited. After reviewing the latest published articles and summarizing the cases in our hospital， we advocate surgery and post-surgical radiation as the primary treatment modality. As for chemotherapy， the potential survival benefit remains controversial.

Key words: synovial sarcoma, chromosome fusion, surgery, radiotherapy, chemotherapy

摘要： 摘要：滑膜肉瘤占所有软组织肉瘤的6%～9%，多发生于下肢及躯干部位，且多见于关节旁软组织内，病变恶性程度较高，有其特定的病理诊断标准及分子发病机制。由于存在不同亚型及病变发展较为迅速，对手术医生、放化疗医生而言，滑膜肉瘤的治疗仍是较大的挑战。位于头颈部原发的滑膜肉瘤较为少见，仅占所有滑膜肉瘤病例的3%～5％，因此对于其临床病理资料的研究也较少。通过查阅最新文献资料及回顾我院的头颈部滑膜肉瘤病例资料，我们认为手术+术后放疗的方法仍可做为滑膜肉瘤的首选治疗方法。但对于化疗治疗效果，仍需进一步评价。

关键词: 滑膜肉瘤, 染色体融合, 手术, 放疗, 化疗