Abstract: Abstract：Objective To study the clinical effect on patients with generalized aggressive periodontitis who accepted periodontal systematic therapy for 5 years. Methods Ten patients with generalized aggressive periodontitis were selected in the Periodontology and Oral Mucosa Department，Stomatological Hospital of Dalian from January 2006 to January 2007. These patients accepted periodontal systematic therapy for 5 years，including：periodontal initial therapy，periodontal surgical therapy，and periodontal supportive therapy. Clinical parameters of probing depth(PD)，clinical attachment level(CAL)，tooth mobility(TM)and bleeding on probing(BOP)were recorded by Florida electronic probe at baseline and 1-5 years after therapy，then analysis was carried out. Panoramic tomogram and the first molar intraoral radiography were detected before and 5 years after therapy. Results PD and CAL were decreased 1-5 years after periodontal systematic therapy，the positive sites of BOP were reduced and TM was improved. The statistical differences were detected(P < 0.01). The positive sites of BOP were reduced in the 5th year than in 1-3years，and the statistical differences were detected(P < 0.05). Conclusion To generalized aggressive periodontitis，the effect of periodontal systematic therapy of 5 years is effective and stable.

Key words: generalized aggressive periodontitis, periodontal systematic therapy

摘要： 摘要：目的 探讨广泛型侵袭性牙周炎患者接受5年牙周系统治疗的临床疗效。方法 选择2006年1月至2007年1月在大连市口腔医院牙周黏膜科就诊的广泛型侵袭性牙周炎患者10例，进行5年的牙周系统治疗(牙周基础治疗、牙周手术治疗和牙周支持治疗)，在牙周治疗前、牙周治疗后1 ~ 5年采用Florida探针检查记录探诊深度(PD)、附着丧失(CAL)、牙齿松动度(TM)、探诊出血(BOP)等临床指标，并进行统计分析。在治疗前和治疗后5年拍摄曲面断层片和第一磨牙的根尖片。结果 牙周系统治疗后1 ~ 5年的PD、CAL均较治疗前有明显降低，BOP阳性位点较治疗前明显减少，TM较治疗前有明显改善，差异均有统计学意义(P < 0.01)。治疗后5年较治疗后1 ~ 3年的BOP阳性位点明显减少，差异均有统计学意义(P < 0.05)。结论 广泛型侵袭性牙周炎患者经牙周系统治疗5年的临床疗效良好且稳定。

关键词: 广泛型侵袭性牙周炎, 牙周系统治疗