关键词: 妊娠, 牙周炎, 早产, 小于胎龄儿

Abstract: Objective    To study the correlations between maternal periodontitis and preterm birth，small for gestational age children. Methods    By prospective study，the data of 3251 pregnant women from 2009.01 to 2009.04 for routine oral examination in Hubei Mother and Children Hospital，whose  oral examination in mid-pregnancy included debris index，sulcus bleeding，periodontal pocket probing depth and clinical attachment loss levels，were entered into the database，and they were followed with pregnancy outcomes of birth weight and birth gestational age. Chi-square test and logistic regression analysis of statistical methods were used for data analysis. Results    Totally 2702 cases of pregnancy women were eligible，and 301 cases of pregnancy women were diagnosed with periodontitis，of which 61 cases were severe. The rates of preterm birth and small for gestational age children in the cases of severe periodontitis were 11.5% and 9.8%，but the rates were 6.0% and 6.6% in normal oral pregnancy women，the difference being statistically significant（P < 0.001）. The average termination of pregnancy gestational age and weight were 35.2 weeks and 2478 g，but 39.3 weeks and 3512 g in oral normal pregnant women，the difference being statistically significant（P < 0.001）. The OR values were 2.45 and 3.47，respectively. Conclusion    Maternal severe periodontitis is one of the major risk factors for premature and small for gestational age children.

Key words: pregnancy, periodontitis, premature, small for gestational age