中国实用口腔科杂志 ›› 2025, Vol. 18 ›› Issue (3): 351-357.DOI: 10.19538/j.kq.2025.03.015

• 综述 • 上一篇    下一篇

异种胶原基质Mucograft在牙周软组织增量中的应用研究进展

王毓佳1,张洪波2,吴迎涛2   

  1. 1. 山东第二医科大学,山东 潍坊 261000;2. 青岛大学附属青岛市口腔医院,山东 青岛 266000
  • 出版日期:2025-05-30 发布日期:2025-05-30
  • 通讯作者: 吴迎涛
  • 基金资助:
    山东省医药卫生口腔内科学重点学科项目(2025-2027);青岛市医疗卫生重点学科建设项目(2025-2027);青岛市口腔疾病临床医学研究中心项目(22-3-7-lczx-7-nsh)

  • Online:2025-05-30 Published:2025-05-30

摘要: 软组织增量是牙周组织或种植体周组织进行软组织重建的方法。目前临床实践中,冠向复位瓣、结缔组织移植术、游离龈移植术等治疗方法被广泛采用,但这些自体组织移植方法存在第二创口、手术时间长、术后疼痛发生率高等缺点,因而替代材料的研发受到广泛关注。Mucograft作为一种新型的异种胶原基质材料,因具有减少第二创口、缩短手术时间及降低术后疼痛等优势,成为近期研究热点。文章就Mucograft在牙周软组织增量中的研究进展做一综述,以探讨其在临床应用中的优势与挑战。

关键词: 软组织增量, 结缔组织移植, 冠向复位瓣, Mucograft, 异种胶原基质

Abstract: Soft tissue augmentation is a method for soft tissue reconstruction in periodontal tissue or peri-implant tissue. Currently in clinical practice,the coronally advanced flap(CAF),connective tissue graft(CTG)and free gingival graft(FGG)are the common therapies widely used. However,autologous soft tissue transplantation has several drawbacks,such as the presence of a secondary wound,prolonged surgical time and a high incidence of postoperative pain. The development of alternative materials has garnered widespread attention. Mucograft,a new type of xenogeneic collagen matrix material,has become a focus of recent research due to its advantages of reducing a second wound,shortening surgical time and decreasing postoperative pain. This review focuses on the research progress in Mucograft in peridontal soft tissue augomentation,aiming to discuss its advantages and challenges in clinical application.

Key words: soft tissue augmentation, connective tissue graft, coronally advanced flap, Mucograft, xenogeneic collagen matrix