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02 June 2018, Volume 34 Issue 6 Previous Issue    Next Issue

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Comprehensive quality management of clinical technology of assisted reproduction. HU Lin-li，SUN Ying-pu 2018, 34(6): 581-583.  DOI: 10.19538/j.fk2018060102 Abstract ( )   To establish a clinical quality management system of Assisted reproductive technology is the use of standardized quality management tools，standardized control ling the personnel，equipment，materials，environment and system.Through the implementation of quality，risk，process management，achieving quality control，assurance and improvement.It is an important measure to improve the level of human assisted reproductive technology and promote the development of technology.

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Setting requirements of IVF laboratory. HAN Shu-biao，HUANG Guo-ning 2018, 34(6): 583-586.  DOI: 10.19538/j.fk2018060103 Abstract ( )   The main function of IVF laboratory is for  the in vitro operation and culture of human gametes/embryos.IVF laboratory setting plays a crucial role for the successful assisted reproductive technology.The air quality，temperature and humidity，as well as the configuration of equipment will affect the development and implantation of the embryos as well as the safety of the fetus.This paper will focus on the key setting of IVF laboratory.

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Prevention of adverse accidents in vitro fertilization laboratory. DING Chen-hui，XU Yan-wen 2018, 34(6): 586-591.  DOI: 10.19538/j.fk2018060104 Abstract ( )   Reducing medical errors，thus to improve our service for infertile patients, is the main goal for all medical staffs in ART field.Prevention of adverse incidents is one of the key points of controlling medical errors.This paper introduced current situation and problems faced in management of adverse incidents based on latest information. Principals and strategies to prevent adverse  incdients were sumarized.We hope to promote the healthy development of ART in China.

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Quality control of human embryo laboratory system. SUN Zheng-yi 2018, 34(6): 591-594.  DOI: 10.19538/j.fk2018060105 Abstract ( )   The main objective of an IVF center is to provide good service for infertile couples.One of the key factors contributing to this outcome is the performance of the embryo laboratory，where embryos of the patients developed.Only embryos with good viability can achieve successful pregnancy.It is now becoming increasingly evident that embryo and its later development can be affected by external conditions during oocytes development and sperm collection.The development and viability of embryos in vitro is affected by contaminants and relatively small ?uctuations in the environment，such as VOCs，environment temperature，concentration of CO2 and pH.The purpose of quality control activities in IVF laboratory is to ensure reproducibility of all methods and operations in order to provide consistent and optimal conditions for the embryo culture.

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Risk management in preimplantation genetic diagnosis. XU Yan，XU Yan-wen 2018, 34(6): 595-598.  DOI: 10.19538/j.fk2018060106 Abstract ( )   With the rapid development of preimplantation genetic diagnosis（PGD）technology in the past 20 years，the possible problems and risks have arisen at the same time.Attention should be paid to the problems from genetic counseling，embryo culture，embryo biopsy to genetic diagnosis.Allele drop-out and mosaicism in early stage of embryo were the main risk factors of misdiagnosis in current PGD methods.This paper analyzed the risk factors and coping measures in every step of PGD.

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General health and mental health of offspring after assisted reproductive technology. SHI Yu-hua，CHEN Zi-Jiang 2018, 34(6): 598-601.  DOI: 10.19538/j.fk2018060107 Abstract ( )   Safety of assisted reproductive technology（ART）especially its effect on the general and mental health of ART offspring has been one of the focuses in recent years.Most studies have shown that the health state of children born from ART treatment is similar to that of naturally conceived children，suggesting ART is a relatively safe technology.There is an urgent need for long-term follow-up studies of IVF-conceived children，as it is too difficult to determine whether the observed associations demonstrated are related to the genetic origin of the children，or are related to the infertility per se，the IVF treatment per se，or the adverse obstetric outcomes associated with IVF treatment.

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Application of PDCA cycle in the field of ART： with the example of embryo contamination. LIU Jian-qiao，WU Yi-xuan 2018, 34(6): 602-605.  DOI: 10.19538/j.fk2018060108 Abstract ( )   PDCA cycle is widely used in all the fields now.Management of medical quality and safety is very important during the medical service，expecially in the field of Assisted Reproductive Technology（ART）.In this reseach，we demonstrated the application of PDCA cycle in the field of ART for quality control，with the example of embryo contamination.

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Influence of vaginal microecological environment on the safety of the assisted reproductive technology. ZHANG Di-kai，LI Jia-chen 2018, 34(6): 605-608.  DOI: 10.19538/j.fk2018060109 Abstract ( )   Although assisted reproductive technology（ART）is the core technology of infertility treatment，the true reproductive capacity of women depends mainly on the quality of the oocyte and the maternal environment that supports implantation and ongoing development of the conceptus.Vaginal microecological environment is an important evaluation indicator of female reproductive health，which is related to female infertility and pregnancy outcome.In the process of ART implementation，vaginal microecological environment changes with controlled ovarian stimulation，operation，endometrial preparation and pregnancy status.These changes have certain impact on the ART outcomes.It is worth noting that the vaginal microecological environment provides a new direction for infertility patients to get a better outcome by strengthening the safety of assisted reproductive technology.

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Establish a rigorous management system of assisted reproductive technology on ethics and regulations. ZHANG Yun-shan，YANG Kun 2018, 34(6): 608-612.  DOI: 10.19538/j.fk2018060110 Abstract ( )   With continuous standardization of reproductive medicine institutions，the ethics and regulations as well as management of assisted reproductive technology and sperm bank are gradually established，with strong government dominance.The corresponding ethical principles，administrative rules and management system have been established primarily at present.But some original regulations have to be revised due to the rapid development and constantly expanding scale of assisted reproductive technology and there has to be new regulations and rules to solve new problems.It is advised to normalize the practice and behavior of related personnel including patients on a broader level for the reason that the old regulations and rules are usually not so appropriate.In conclusion，we had better make inventions and innovations to promote the development of assisted reproductive legislation to higher level.