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01 January 2017, Volume 33 Issue 1 Previous Issue    Next Issue

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Age and ovary function and ovarian aging. CHEN Ying,YU Qi 2017, 33(1): 68-70.  DOI: 10.19538/j.fk2017010116 Abstract ( )   The female fertility reaches the peak in the middle and late stage of 20 to 30 years old.Since then，it gradually reduces， and comes to the end at menopause.Decreased fertility ability could happen before FSH levels rise， inhibin B declines and menstrual cycle length changes.Antimullerian hormone（AMH）is a marker that can predict the decline of ovarian reserve earlier than inhibin B.Changes in the number of antral follicles and menstrual cycle length variability could also reflex reproductive aging acceleration.Reproductive aging is inevitable in population.However，aging process for each individual is affected by the interaction of a variety of complex factors.

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Gametes of advanced age couple LI Gang， SUN Ying- pu 2017, 33(1): 70-74.  DOI: 10.19538/j.fk2017010117 Abstract ( )   Age is an important index of human fertility potential， whether in spontaneous conception or in assisted reproductive technology.Along with the carrying out of the Two- child Policy， an increasing number of advanced age couples consult reproductive medicine doctors so as to conceive a baby.To conceive and deliver a baby at an advanced age is challenging，so many aspects need to be taken into consideration；for example， whether their physical fitness enables them to be pregnant， maternal and infant complications during pregnancy， congenital genetic defects and so on.It’ s essential to inform patients that advanced age may relate to unsuccessful trial ofassisted reproductive technology and the increased risk of obstetric and neonatal complications.Age-related decrease of gamete quality is the key factor，which may lead to the high risk of fertility of advanced age couples.This article comments on the problems of advanced age-related gametes.

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Safety of the offspring of natural conception and assisted reproductive technology in women at advanced age. WEI Jing- zan，WANG Xiu- xia 2017, 33(1): 74-78.  DOI: 10.19538/j.fk2017010118 Abstract ( )   In recent years， with the delay of the reproductive age， the demand for elderly pregnancy and assisted reproductive technology is increasing， and the safety of the offspring is also getting more and more attention.For women at advanced age， knowing how to reduce the risk of birth defects and avoid risks in order to achieve the purpose of eugenics is the premise to understand the risk of natural conception and assisted reproductive technology of them.Therefore， this article will make a summary of the birth defects of the off?spring of natural conception and assisted reproductive technology in women at advanced age.

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Clinical management in ART laboratory for patients of poor ovarian response XU Yan-wen 2017, 33(1): 78-81.  DOI: 10.19538/j.fk2017010119 Abstract ( )   With the promulgation of second- child policy in China， more and more patients with poor ovarian reserve might seek the help of assisted reproductive technology （ART）， which not only increases the burden of ART lab， but also decreases clinical pregnancy rate.This paper described the possible strategy to increase the pregnancy outcome of patients of poor ovarian response in ART lab.

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Clinical approaches to poor ovarian responders in assisted reproductive technology. YUAN Yuan，ZHOU Can-quan 2017, 33(1): 81-85.  DOI: 10.19538/j.fk2017010120 Abstract ( )   With the dramatic growth of number of advance- aged women who seek to have a child， poor ovarian response becomes a frequently encountered challenge for physicians practicing reproductive medicine.Adjusting the controlled ovarian hyperstimulation protocols， using adjuvants during controlled ovarian stimulation， and proper pre-disposal treatment are the common approaches to this issue.Selecting from these methods and formulating an individualized protocol for a specific patient to achieve the best clinical outcomes is a tricky task for all the physicians practicing reproductive medicine.

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Management of common gynecological problems in women at advanced age to get pregnant. LIANG Zheng，LIN Jun 2017, 33(1): 85-89.  DOI: 10.19538/j.fk2017010121 Abstract ( )   At present， it is more common for women at advanced age to get pregnant， especially for those who are over 40 or even 45 years old.Apart from the high risk of pregnancy due to their age， these older women are also faced with certain gynecological problems，such as uterus myomas， ovarian cysts， cervical lesions，previous cesarean scar defects and so on.The frequently asked questions concentrate on whether the illness or situation allows a pregnancy， when to treat it， how to monitor it and what its influence is on the mode of delivery.This review is aimed to answer these questionson the basis of related literatures.

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Treatment for common internal diseases in women advanced maternal age preparing for pregnancy. LIN Jian- hua， ZHUANG Xu 2017, 33(1): 89-93.  DOI: 10.19538/j.fk2017010122 Abstract ( )   With the growth of age,the variations in the metabolism and decrease in the elasticity of blood vessels lead to the growing incidence of cardiovascular diseases， diabetes mellitus， kidney disease， thyroid disease and so on， which are associated with the risk of maternal- fetal health during the pregnancy， so essential pre-pregnancy interventions are more important.

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Re- pregnancy in advanced maternal age with scar uterus. FEI Kui- lin,ZHANG Wei- she 2017, 33(1): 93-96.  DOI: 10.19538/j.fk2017010123 Abstract ( )   With the implemention of two-child policy in China， there are more and more women at advanced maternal age with scarred uterus， caused by different factors.Because the features of uterine scars are different due to different causes and operation options， the timing， monitoring and risks during re-pregnancy are different.This paper aims to discuss common problems relating to re-pregnancy with scarred uterus， providing helpful references for obstetrical workers.

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Management of pregnant women at advanced maternal age. ZHAO Jie，FENG Ling. 2017, 33(1): 96-99.  DOI: 10.19538/j.fk2017010124 Abstract ( )   Abstract：In recent years，the number of pregnant women at advanced maternal age has increased very quickly，followed by the increase of maternal and neonatal morbidity and mortality.It is the key to guaranteeing these womens health，decreasing incidence of birth defects and improving obstetrical quality to perfect pre-pregnant consultation and evaluate the risk in gestation period，strengthen the screening and diagnosis of birth defects in early pregnancy，strengthen the management of catastrophe placenta previa and vaginal birth after cesarean section（VBAC）in whole pregnancy.