Abstract: Pathogenic microorganisms can gain access to the uterine cavity by ascending from the lower reproductive tract or via placenta transmission，and may result in many adverse maternal and infant outcomes，including miscarriage，stillbirth，premature delivery，congenital defects and long-term sequelae.The more common causes of infection include sexually transmitted infections，classic "TORCH" infections and some emerging infectious diseases.This article refers to the latest international researches and guidelines to explain the mechanism of intrauterine infection，maternal-infant outcomes and intervention measures，so as to optimize the pregnancy management of intrauterine infections.

Key words: intrauterine infection, sexually transmitted infections, pathogen infection, maternal and infant outcomes

摘要： 病原微生物可以通过下生殖道或胎盘传播进入宫腔，并可能导致多种不良的母婴结局，如流产、死产、早产、先天缺陷和远期后遗症等。其中较常见的感染来源包括性传播感染、经典的“TORCH”感染及一些新兴传染病。文章参考国际上最新研究和指南，对宫内感染机制、母婴结局及干预对策进行阐述，以优化宫内感染的孕期管理。

关键词: 宫内感染, 性传播感染, 病原体感染, 母婴结局