Acta Metallurgica Sinica

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Clinical significance of sentinel lymph node mapping in endometrial carcinoma.

  

  1. Department of Obstetrics & Gynecology,Southwest Hospital,Third Military Medical University,Chongqing 400038,China
  • Online:2017-05-02 Published:2017-05-08

前哨淋巴结检测在子宫内膜癌中的临床意义

  

  1. 第三军医大学西南医院妇产科,重庆 400038
  • 通讯作者: 梁志清

Abstract:

Lymph node removal for staging,as part of the initial surgical management for patients with endometrial carcinoma,remains a controversial topic in gynecologic oncology. With the lack of prospective trials demonstrating a survival benefit for extensive lymphadenectomies,the rise of the minimally invasive surgical approach,and the increasing availability of novel near-IR imaging technologies and pathologic ultrastaging,lymphatic mapping has emerged as an increasingly popular option over the last few years.The clinical studies also showed its good prospect of application.However,the injection position and marker selection,paraaortic sentinel lymph node sampling,and other aspects also were faced with many problems.Therefore,it still needs further study whether sentinel lymph node mapping can replace endometrial cancer staging surgery.

Key words: endometrial neoplasm, sentinel lymph node, sentinel lymph node mapping, pathologic ultrastaging

摘要:

子宫内膜癌患者手术是否清扫盆腔和腹主动脉旁淋巴结尚存在争议。在缺乏前瞻性临床试验证实淋巴结清扫可以改善临床预后前提下,随着精准治疗与微创治疗理念的兴起,最新的近红外光谱技术、超分期技术的应用,近年来子宫内膜癌前哨淋巴结检测技术发展迅速,临床研究结果也显示了其良好的应用前景,但是在具体注射部位、示踪剂选择、腹主动脉周围前哨淋巴结采样等环节也面临较多问题,前哨淋巴结检测能否替代子宫内膜癌全面分期手术,仍需进一步研究。

关键词: 子宫内膜肿瘤, 前哨淋巴结, 前哨淋巴结检测, 病理学超分期

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