Abstract:

The disparate genetic alterations of aggressive subtype of endometrial cancer determine its specificities in terms of clinical features，extent of surgery，clinical prognosis and other aspects. Clinicians should raise awareness of this specific subtype of endometrial cancer.Careful initial evaluation，comprehensive surgical staging and adjuvant therapy with platinum-based chemotherapy combined with tumor-directed radiotherapy should be performed to improve the prognosis.

Key words: endometrial neoplasm, aggressive subtype, initial evaluation, surgical staging, adjuvant therapy after surgery

摘要：

特殊类型子宫内膜癌的病理分型及内在分子病理改变，决定其在临床表现、手术范围、临床预后等方面均与子宫内膜样腺癌有所区别。临床医生应提高对特殊类型子宫内膜癌的认识，术前仔细评估，手术全面彻底，术后辅以紫杉醇+铂类为基础的化疗及靶向放疗等综合治疗以改善患者预后。

关键词: 子宫内膜肿瘤, 特殊类型, 治疗前评估, 分期手术, 术后辅助治疗