Abstract:

Abstract:Persistent cervical infection with high-risk human papillomavirus（HPV） genotypes is the main cause of the development of cervical cancer and precancer.HPV detection effectively improves the sensitivity of cervical cancer detection and becomes an important method of cervical cancer screening.However，due to wide variety of HPV detection methods，differences among various detection methods，principles and clinical cut-off value and so on，clinicians tend to have some misunderstandings in their clinical application.

Key words: human papillomavirus（HPV）, cervical cancer, cervical precancer

摘要：

高危型人乳头瘤病毒（HPV）的持续感染是宫颈癌和宫颈癌前病变发生的重要原因，HPV检测有效地提高了宫颈癌筛查的敏感度，是宫颈癌筛查的重要方法。但由于HPV检测方法众多，各种检测方法的设计、原理以及临床阳性阈值设定存在差异等因素，临床应用中容易存在误区。

关键词: 人乳头瘤病毒, 宫颈癌, 宫颈癌前病变