Abstract: The spectrum of fetal middle cerebral artery （MCA）reflects the early adaptation of fetal cardiovascular system to hypoxia or blood flow redistribution，and its measurement requires standardization，which has become one of the hot spots of clinical application of fetal hemodynamics in recent years. Recently，a number of retrospective and prospective clinical studies with large samples have reported the assessment indicators of MCA，the range of reference values and the cut-off values applied to various clinical diseases. Based on the ISUOG fetal Doppler flow spectrum monitoring guidelines（2021），this paper analyzes and summarizes high-quality studies related to fetal MCA spectrum，and provides reference for its standardized clinical application.

Key words: fetal middle cerebral artery, high-risk pregnancy, standardized measurement, placental insufficiency

摘要： 胎儿大脑中动脉（MCA）血流频谱反映了其心血管对缺氧或血流再分布的早期适应，其测量要求标准化、规范化，是近年来胎儿血流动力学临床应用研究的热点之一。国内外近期出现了一些大样本的回顾性及前瞻性临床研究，对MCA评估指标、参考值范围以及临床各疾病中运用的截断值进行了报道。文章结合2021年版国际妇产科超声学会（ISUOG）胎儿多普勒血流频谱监测指南，对胎儿MCA血流频谱相关的高质量研究进行分析总结，为其临床规范化运用提供参考。

关键词: 胎儿大脑中动脉, 高危妊娠, 规范化测量, 胎盘灌注不足