Abstract:

Abstract： Objective To explore clinical characteristics of dysfunctional uterine bleeding in hospitalized patients of different ages. Methods Total 158 hospitalized patients from March 2009 to February 2014 in our hospital whose main diagnosis was dysfunctional uterine bleeding （DUB） were collected and retrospectively analyzed. The patients' general information,such as routine blood tests，ultrasound and clinical endometrial pathological data were collected for analysis. Results The 158 cases were divided into 3 different age groups. According to the degree of anemia，most severe anemia occurred in≤30 year-old group （46.9%），followed by ＞40 year-old group （32.9%）.in >30～40 year-old group the percentage was the lowest（27.3%）. The difference among three groups was statistically significant（P=0.03）. Blood transfusion rates of the three groups had statistically significant difference（P=0.001）.Transfusion rate in ≤30 year-old group reached 71.4%. Among different age groups，endometrial thickness and abnormal endometrial hyperplasia rates had no statistical differences （P>0.05）.However,abnormal endometrial hyperplasia rates between different endometrial thickness groups were statistically different（P = 0.014）. In the endometrial thickness ＞12 mm group，abnormal endometrial hyperplasia rate was 53.3% and in ＜5 mm group there was no case of endometrial hyperplasia. Conclusion The clinical anemia degree of DUB hospitalized patients is significantly related to age. Endometrial thickness plays an important role in predicting the abnormal endometrial hyperplasia.

Key words: dysfunctional uterine bleeding, anemia, endometrial thickness, endometrial hyperplasia

摘要：

目的 探讨不同年龄段功能失调性子宫出血（功血）住院病人临床特点。方法　收集2009年3月至2014年2月间因确诊功血为主要诊断而入住中山大学附属第一医院的病人158例。收集病人年龄等一般情况、血常规、B超及诊刮内膜病理资料进行分析。158例病人分为3个年龄组按照贫血程度比较。结果　≤30岁住院病人发生重度贫血占46.9%，其次为＞40岁组（32.9%）。>30～40岁组最低（27.3%），3组间比较，差异有统计学意义（P=0.03）。3组间输血率比较，差异亦有统计学意义（P=0.001），≤30岁病人住院输血比例达到71.4％。不同年龄组间子宫内膜厚度及内膜异常增生情况比较，差异无统计学意义（P＞0.05）。不同子宫内膜厚度组间内膜异常增生率差异有统计学意义（P=0.014），在子宫内膜厚度超过12mm组，内膜异常增生率达53.3%，而＜5mm组无子宫内膜异常增生发生。结论　功血住院病人的贫血情况和年龄明显相关；子宫内膜厚度对预测子宫内膜异常增生有重要作用。

关键词: 功能失调性子宫出血, 贫血, 子宫内膜厚度, 子宫内膜增生