Surgical treatment for the recurrent cervical cancer.

doi:10.7504/fk2015050109

Abstract

Abstract:

Despite many disputes for the treatment of recurrent cervical cancer，surgery is still one of the crucial methods to extend the life of patients and have the possibility to treat the recurrence radically.This review will classify the recurrence cervical cancer on the basis of radiotherapy history and recurrence location.Furthermore we will describe different types of surgery and their application for various types of recurrence cervical cancer，and will focus on the latest progress of pelvic exenteration.

Key words: recurrent cervical cancer, pelvic exenteration, laterally extended endopelvic resection

摘要：

尽管宫颈癌复发的治疗策略有诸多争议，但手术依然是延长晚期患者生命、甚至有机会根治肿瘤的重要手段之一。文章将依据既往放疗与否和病灶位置对宫颈癌复发分类，并阐述不同类型宫颈癌复发后的手术适应证，同时将重点介绍盆腔器官清除术对于放疗后盆腔局部复发的治疗作用。

关键词: 宫颈癌复发, 盆腔廓清术, 侧向延伸的盆腔内切除术

CLC Number:

R737.3

HAN Xiao-tian,WU Xiao-hua.. Surgical treatment for the recurrent cervical cancer.[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2015050109.

韩啸天，吴小华. 宫颈癌复发后的手术治疗[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2015050109.

References

［1］    International Agency for Research on Cancer.Cervical Cancer Estimated Incidence，Mortality and Prevalence Worldwide in 2012.World Health Organization，2012.Available at: http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx?cancer=cervix.

［2］   Perez CA，Grigsby PW，Nene SM，et al.Effect of tumor size on the prognosis of carcinoma of the uterine cervix treated with irradiation alone［J］.Cancer，1992，69:2796-2806.

［3］   Marchiolé P，Buénerd A，Benchaib M，et al.Clinical significance of lympho vascular space involvement and lymph node micrometastases in early-stage cervical cancer: a retrospective case-control surgico-pathological study［J］.Gynecol Oncol，2005，97(3):727-732.

［4］   Mangler M，Lanowska M，Kohler C，et al.Pattern of cancer recurrence in 320 patients after radical vaginal trachelectomy［J］.Int J Gynecol Cancer，2014，24:130-134.

［5］   Smaniotto D，D'Agostino G，Luzi S，et al.Concurrent 5-fluorouracil，mitomycin C and radiation with or without brachytherapy in recurrent cervical cancer: a scoring system to predict clinical response and outcome［J］.Tumori，2005，91(4):295-301.

［6］   Coleman RL，Keeney ED，Freedman RS，et al.Radical hysterectomy for recurrent carcinoma of the uterine cervix after radiotherapy［J］.Gynecol Oncol，1994，55(1):29-35.

［7］   Peiretti M，Zapardiel I，Zanagnolo V，et al.Management of recurrent cervical cancer: a review of the literature［J］.Surg Oncol，2012，21:59-66.

［8］   Berek JS，Howe C，Lagasse LD,et al.Pelvic exenteration for recurrent gynecologic malignancy: survival and morbidity analysis of the 45-year experience at UCLA［J］.Gynecol Oncol，2005，99:153-159.

［9］   Chiva LM，Lapuente F，Gonzalez-Cortijo L，et al.Surgical treatment of recurrent cervical cancer: state of the art and new achievements［J］.Gynecol Oncol，2008，110:S60-66.

［10］   Soper JT，Havrilesky LJ，Secord AA，et al.Rectus abdominis myocutaneous flaps for neovaginal reconstruction after radical pelvic surgery［J］.Int J Gynecol Cancer，2005，15:542-548.

［11］   Salom EM，Mendez LE，Schey D，et al.Continent ileocolonic urinary reservoir(Miami pouch): the University of Miami experience over 15 years［J］.Am J Obstet Gynecol，2004，190(4):994-1003.

［12］   Karen KL，Chan RN.Advances in surgical treatment of cervical cancer［J］.Women Health，2008，4:245-256.

［13］   Köhler C，Tozzi R，Possover M，et al.Explorative laparoscopy prior to exenterative surgery［J］.Gynecol Oncol，2002，86(3):311-315.

［14］   Mourton SM，Sonoda Y，Abu-Rustum NR，et al.Resection of recurrent cervical cancer after total pelvic exenteration［J］.Int J Gynecol Cancer，2007，17(1):137-140.

［15］   Ang C，Bryant A，Barton DP，et al.Exenterative surgery for recurrent gynaecological malignancies［J］.Cochrane Database Syst Rev，2014，2:CD010449.

［16］    张志毅，臧荣徐，龚沂.盆腔脏器清除术相关的解剖要点和手术技巧［J］.中国实用妇科与产科杂志，2009，3: 187-190.

［17］   H?ckel M，Sclenger K，Hamm H，et al.Five-year experience with combined operative and radiot herapeutic treatment of recurrent gynecologic tumors in filtrating the pelvic wall［J］.Cancer，1996，77:1918-1933.

［18］   Gemignani ML，Alektiar KM，Leitao M，et al.Radical surgical resection and high-dose intraoperative radiation therapy (HDR-IORT) in patients with recurrent gynecologic cancers［J］.Int J Radiat Oncol Biol Phys，2001，50(3):687-694.

［19］   Hockel M，Horn LC，Einenkel J.(Laterally) extended endopelvic resection: surgical treatment of locally advanced and recurrent cancer of the uterine cervix and vagina based on ontogenetic anatomy［J］.Gynecol Oncol，2012，127:297-302.

［20］   Perez CA，Grigsby PW，Camel HM，et al.Irradiation alone or combined with surgery in stage IB，IIA，and IIB carcinoma of the uterine cervix: update of a nonrandomized comparison［J］.Int J Radiat Oncol Biol Phys，1995，31:703-716 .

［21］    Meads C，Davenport C，Malysiak S，et al.Evaluating PET-CT in the detection and management of recurrent cervical cancer: systematic reviews of diagnostic accuracy and subjective elicitation［J］.BJOG，2014，121:398-407.

［22］   Gadducci A，Tana R，Cosio S，et al.Treatment options in recurrent cervical cancer (Review)［J］.Oncol Lett，2010，1:3-11.

［23］    Schmidt AM，Imesch P，Fink D，et al.Indications and long-term clinical outcomes in 282 patients with pelvic exenteration for advanced or recurrent cervical cancer［J］.Gynecol Oncol，2012，125:604-609.

［24］   Yamamoto K，Yoshikawa H，Shiromizu K，et al.Pulmonary metastasectomy for uterine cervical cancer: a multivariate analysis［J］.Ann Thorac Surg，2004，77(4):1179-1182.

［25］   Lapitan MC，Buckley BS.Impact of palliative urinary diversion by percutaneous nephrostomy drainage and ureteral stenting among patients with advanced cervical cancer and obstructive uropathy: a prospective cohort［J］.J Obstet Gynaecol Res，2011，37:1061-1070.

［26］    Perri T，Korach J，Ben-Baruch G，et al.Bowel obstruction in recurrent gynecologic malignancies: Defining who will benefit from surgical intervention［J］.Eur J Surg Oncol，2014，40:899-904.

（2015-02-20收稿）