Assisted reproductive technology and AIDS.

doi:10.7504/fk2014080108

Abstract

Abstract:

Abstract: Assuring that HIV-affected couples can acquire the preconception counseling and antiviral therapy during pregnancy is crucial in decreasing both mother-to-child HIV transmission and infection of seronegative partners. The transmission risk of HIV virus can be greatly reduced by sperm-washing procedure in HIV positive male. HIV infection and antiviral treatment may have negative effect on female fertility and assisted reproduction outcome，especially of the oocyte quality. It might be related to mitochondrial dysfunction as a result of the use of antiretroviral drugs.

Key words: assisted reproduction technology, human immunodeficiency virus, vertical transmission

摘要：

对于有生育要求的艾滋病家庭，应加强孕前咨询，孕前及孕期的抗病毒治疗对于降低垂直传播风险至关重要。利用密度梯度和上游法对人类免疫缺陷病毒（HIV）男性感染者精液进行体外处理，可极大降低HIV的传播风险。HIV感染和抗病毒治疗会造成女性生育力下降，且引起卵母细胞的线粒体损伤，影响辅助生殖结局。

关键词: 辅助生殖技术, 人类免疫缺陷病毒, 垂直传播

CLC Number:

R759

ZHENG Xiao-ying,WANG Hai-yan.. Assisted reproductive technology and AIDS.[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2014080108.

郑晓英，王海燕. 辅助生殖技术与艾滋病[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2014080108.

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（2014-05-18收稿）

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