摘要:
原发女性生殖系统恶性黑色素瘤(malignant melanoma, MM)是少见的皮肤恶性肿瘤,在过去的30年里MM的发病率有显著的增加,占恶性黑色素瘤的0.23%。因生殖系统恶性黑色素瘤国内外现均无诊疗指南,其预后与肿瘤分级的因素与皮肤恶性肿瘤相似,所以,美国癌症分期联合委员会(AJCC)建议使用恶性黑色素瘤分级系统作为女性生殖系统恶性黑色素瘤评估肿瘤分级的工具,并且认为其治疗手段与皮肤恶性肿瘤相似。由于MM预后因素的不确定性,临床研究的样本量过少,所以,新治疗手段的临床应用及发展均受限制。目前MM的治疗主要包括有:手术、放化疗、免疫治疗及靶向治疗。局部手术是基本治疗方法,早期可单行手术治疗或加行辅助治疗,晚期或已有肿瘤转移可行手术加辅助治疗,但各类辅助治疗的个体差异较大。
中图分类号:
高浩成,龚美琴,高雪梅. 女性生殖系统恶性黑色素瘤治疗现状[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2015010119.
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