中国实用妇科与产科杂志

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子宫内膜异位症不孕与盆腔内环境及表观遗传学的关系

王水英1黄荷凤2   

  1. 作者单位:1.杭州师范大学临床医学院,浙江 杭州310036;2. 浙江大学医学院附属妇产科医院,浙江 杭州310006
  • 出版日期:2013-07-02 发布日期:2013-07-02

  • Online:2013-07-02 Published:2013-07-02

摘要:

子宫内膜异位症(内异症)是一种妇科常见病,不孕是其主要临床表现之一。内异症不孕是多因素共同作用的结果。目前认为,内异症不孕的发生与盆腔内环境的改变密切相关,腹腔液中的多种细胞因子和自由基可能参与其中。另外,异常的表观遗传调控可能与内异症不孕的发生有关。

关键词: 子宫内膜异位症, 不孕, 盆腔内环境, 表观遗传学

Abstract:

Abstract:Endometriosis is a common gynecological disease of reproductive age women and infertility is one of its clinical manifestations. It has shown that infertility in endometriosis is multifactorial and could be associated with altered pelvic environment. Several kinds of cytokines and free radicals in peritoneal fluid are involved in this process. In addition,aberrant epigenetic may be related to the endometriosis-associated infertility.

Key words: endometriosis, infertility, pelvic environment, epigenetic

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