绒毛膜羊膜炎与胎儿及新生儿疾病

doi:10.7504/fk2016050112

摘要/Abstract

摘要：

绒毛膜羊膜炎是产科炎症反应，但与新生儿预后关系密切。母体的宫内炎症反应可以直接导致胎儿和婴儿患病率和死亡率增加，胎儿炎症反应综合征（FIRS）也不可忽视。早期识别和快速诊断有助于减少母儿的近期合并症，改善新生儿的远期预后。产科和儿科共同关注，整合信息，是早期发现、实施有效干预的临床重点之一。

关键词: 炎症因素, 绒毛膜羊膜炎, 胎膜早破, 新生儿疾病

Abstract:

Abstract: Chorioamnionitis as a major risk factor contributes to prematurity-associated mortality and morbidity.Fetal inflammatory response syndrome (FIRS) should not be ignored.Prompt diagnosis can help avert the significant short-term (endometritis，neonatal sepsis and perinatal infections) and long-term consequences (infant’s systemic and neurologic sequelae) .This article aims to summarize the short-term outcomes and long-term sequaelas of chorioamnionitis，and calls for future studies which aim to better understand the mechanism of disease and to develop better detection and intervention methods to prevent the significant associated morbidity.

Key words: inflammatory factors, chorioamnionitis, premature rupture of membranes, neonatal diseases

中图分类号:

R722

韩彤妍，杨孜，朴梅花. 绒毛膜羊膜炎与胎儿及新生儿疾病[J]. 中国实用妇科与产科杂志, DOI: 10.7504/fk2016050112.

HAN Tong-yan，YANG Zi，PIAO Mei-hua.. Chorioamnionitis and fetal and neonatal diseases.[J]. Acta Metallurgica Sinica, DOI: 10.7504/fk2016050112.

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（2016-03-15收稿）