中国实用妇科与产科杂志

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子宫颈癌的规范化诊断

  

  1. 河北医科大学第四医院妇科,河北 石家庄 050011
  • 出版日期:2021-01-02 发布日期:2021-01-14
  • 通讯作者: 康山

Standardized diagnosis of cervical cancer.

  1. The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China
  • Online:2021-01-02 Published:2021-01-14

摘要: 子宫颈癌的规范化诊断是子宫颈癌规范化治疗的先决条件,子宫颈癌的病因明确,其发生发展是一个渐进的过程,并有其鲜明的特点。从HPV的持续感染到子宫颈上皮内瘤变,再到浸润癌一般需要8~10年的时间,这一阶段的诊断重点是通过检测HPV进行筛查,有时会辅助细胞病理学的检查。浸润癌阶段进展快,诊断主要依靠病理组织学活检和影像学检查,如阴道镜、组织学咬检、子宫颈管搔刮、锥切、CT或MRI。前期筛查的主要目的是发现可治疗的、能发展成浸润性癌症的癌前病变,从而降低子宫颈癌的发病率、死亡率以及与治疗相关的并发症;其次是发现早期浸润癌。而在后期浸润癌阶段所采取的所有手段都是为了明确诊断和分期,以便制定合理精准的治疗决策。

关键词: 筛查, 人乳头瘤病毒, 阴道镜, 子宫颈管搔刮, 锥切, 影像学

Abstract: The standardized diagnosis of cervical cancer is a prerequisite for standardized treatment of cervical cancer. The etiology of cervical cancer is clear,and its occurrence and development is a gradual process with its distinctive characteristics. It usually takes 8 to 10 years from continuous HPV infection to intraepithelial neoplasia,and then to invasive cancer. The focus of diagnosis at this stage is to screen through HPV detection,and sometimes assisted cytopathological examination is needed. The stage of invasive cancer progresses rapidly,and the diagnosis mainly depends on histopathological biopsy and radiographic examination,such as colposcopy,histological bite examination,endocervical canal curettage,conization,CT or MRI. The main purpose of pre-screening is to find treatable precancerous lesions that can develop into invasive cancer so as to reduce the morbidity,mortality and treatment-related complications of cervical cancer,and another purpose is to find early invasive cancer. All the methods adopted in the later stage of invasive cancer are to make a clear diagnosis and staging in order to make reasonable and accurate treatment decisions.

Key words: screening, HPV, colposcope, endocervical canal curettage, conization, radiography

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