Abstract: The clinical data of a child with mesenteric histiocytic necrotizing lymphadenitis admitted to the Children's Hospital of Zhejiang University School of Medicine in May 2021 are reported.The case was a male，11 years and 3 months old.He was admitted to our hospital due to "fever for 10 days and abdominal pain for 5 days". He was admitted to the hospital as appendicitis. Necrotizing lymphadenitis of mesenteric histiocytes was confirmed by mesenteric lymph node biopsy. The child recovered after 2 weeks of oral prednisone treatment， temperature turning normal，and his disease has not recurred during the one-year follow-up for 1 year. Histiocytic necrotizing lymphadenitis is rarely characterized by swelling and pain of mesenteric lymph nodes， which leads to difficult diagnosis. Detailed history and appropriate auxillary examination are very important for confirming diagnosis. If necessary， lymph node biopsies should be performed. Choosing the right lymph node for biopsy can reduce the harm to the child patients.

Key words: histiocytic necrotizing lymphadenitis, mesenteric lymph node

摘要： 报告浙江大学医学院附属儿童医院2021年5月收治的1例肠系膜组织细胞坏死性淋巴结炎患儿的临床资料。患儿男，11岁3月龄，以“发热10d、腹痛5d”就诊，以“阑尾炎”诊断收入院。经肠系膜淋巴结活检确诊为肠系膜组织细胞坏死性淋巴结炎，予口服泼尼松治疗2周，体温正常，随访1年未复发。以肠系膜淋巴结肿痛为主要表现的组织细胞坏死性淋巴结炎罕见，诊断困难。详细的病史及合适的辅助检查对诊断非常重要，必要时需进行淋巴结活检。应积极寻找可活检的浅表淋巴结，以减少对患儿的伤害。

关键词: 组织细胞坏死性淋巴结炎, 肠系膜淋巴结