Chinese Journal of Practical Pediatrics ›› 2023, Vol. 38 ›› Issue (6): 419-425.DOI: 10.19538/j.ek2023060604

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Interpretation of ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents with Celiac Disease

  

  1. Children’s Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Hangzhou 310052,China
  • Online:2023-06-06 Published:2023-07-20
  • Supported by:
    国家重点研发计划(2021YFC2701800、2021YFC2701801)

《欧洲儿科胃肠肝病营养学会关于儿童和青少年乳糜泻管理与随访的立场文件》解读

  

  1. 浙江大学医学院附属儿童医院  国家儿童健康与疾病临床医学研究中心,浙江  杭州  310052
  • 通讯作者: 张晨美,电子信箱: chzcm@zju.edu.cn

Abstract: In 2022, the European Society of Paediatric Gastroenterology Hepatology and Nutrition issued a position paper on the management and follow-up of celiac disease in children and adolescents, asking 10 questions considered essential for the management and follow-up of celiac disease, including the need for follow-up, the frequency of follow-up and what should be evaluated, how to evaluate adherence to a gluten-free diet, when to expect catch-up growth, how to handle high levels of anti-tissue glutaminase antibodies, indications for small bowel biopsy, how to evaluate quality of life, how to manage gluten challenge tests in children with unclear diagnosis, how to improve communication with children or parents, and how to carry out transition to adult disease management, and so on. Based on the literature pevidence or expert opinions, 37 recommendation have been made. This paper only introduces the main contents of the position paper.

Key words: celiac disease; gluten-free diet; follow-up, gluten-challenge test; child; adolescents

摘要: 2022年欧洲儿科胃肠肝病营养学会发布了儿童和青少年乳糜泻管理和随访的立场文件,提出了10个被认为是乳糜泻管理及随访中必不可少的问题,包括:进行随访的必要性、随访的频率和应评估的内容、如何评估无麸质饮食的坚持情况、何时期待追赶生长、如何处理高水平抗组织转谷氨酰胺酶抗体、小肠活检的指征、如何评估生活质量、如何管理诊断不明确儿童的麸质激发试验、如何改善与患儿或家长沟通、如何向成人疾病管理过渡等。利用文献证据或专家意见,制定了37项建议。文章仅对该立场文件的主要内容进行解读。

关键词: 乳糜泻, 无麸质饮食, 随访, 麸质激发试验, 儿童, 青少年