Abstract: As an indispensable component in the human body，L-carnitine has important physiological functions and plays an important role in mitochondrial processes，fatty acid metabolism and ATP production. In the state of deficiency，mitochondrial function is damaged，cell metabolism is changed，and the functions of multiple systems in the body are affected，which in turn leads to the emergence of its various diseases. Exogenous L-carnitine supplementation can not only relieve metabolic disorders and disease state related to carnitine deficiency，but also help the body restore carnitine balance and maintain metabolism，energy balance and health. This article summarizes the use of L-carnitine in various diseases by reviewing the previous literature，in order to improve clinicians' understanding of L-carnitine.

Key words: L-carnitine, deficiency, disease

摘要： 左旋肉碱作为人体中不可或缺的成分，具有重要的生理作用，在线粒体脂肪酸代谢和ATP产生过程中发挥重要作用。在缺乏状态下，线粒体功能受损、细胞代谢改变，影响机体多个系统的功能，进而引发多种疾病。外源性补充左旋肉碱不仅可以缓解代谢紊乱和肉碱缺乏症相关的疾病状态，还可以帮助机体恢复肉碱稳态、保持新陈代谢、能量平衡和健康状况。文章通过对既往文献的回顾，对左旋肉碱在各类疾病中的用途进行总结，以提高临床医生对左旋肉碱的认识。

关键词: 左旋肉碱, 缺乏, 疾病