中国实用儿科杂志 ›› 2022, Vol. 37 ›› Issue (10): 728-732.DOI: 10.19538/j.ek2022100603

• 专题笔谈 • 上一篇    下一篇

短肠综合征的营养策略

  

  1. 浙江大学医学院附属儿童医院  国家儿童健康与疾病临床研究中心,浙江  杭州  310052
  • 出版日期:2022-10-06 发布日期:2022-11-11

Nutritional strategies for short bowel syndrome

  1. Children's Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,National Children's Regional Medical Center,Hangzhou  310052,China
  • Online:2022-10-06 Published:2022-11-11

摘要: 短肠综合征是儿童肠衰竭的主要原因,由于手术切除、先天性缺陷或与疾病相关的吸收丧失引起,在常规正常饮食下无法维持蛋白质-能量、体液、电解质以及微量营养素的平衡,需要专门的营养治疗,治疗的目标是促进肠道适应以达到肠道自主,同时保持健康的生长和发育。营养治疗策略是异质的和复杂的,须量身定制。对肠外、肠内和口服营养的类型和持续时间尚无循证建议。提倡阶段化营养管理,肠外营养对于短肠综合征的婴儿和儿童的生存至关重要,谨慎的营养策略对于减少肠外营养持续时间以及降低肠外营养相关并发症发生的风险至关重要,鉴于肠道适应的需要,早期开始最低限度的喂养、根据肠道耐受性逐渐增加肠内营养的量、经口腔喂养以及多样化平衡饮食是必要的。母乳和混合饮食是不错的选择。

关键词: 短肠综合征, 营养, 喂养策略, 适应, 肠外营养, 肠内营养

Abstract: Short bowel syndrome,as the leading cause of pediatric intestinal failure,is due to surgical resection, congenital defects or disease-related loss of absorption,and normal routine diet can not maintain the balance among protein-energy,body fluid,electrolyte and micronutrient. Nutritional management is required to promote intestinal adaptation to achieve gut autonomy while maintaining normal  growth and development. Nutritional strategies are heterogeneous and complicated,and must be tailored,and there are no evidence-based recommendations for the type and duration of parenteral nutrition, enteral nutrition or oral feeding. Parenteral nutrition is critical for the survival of infants and children with short bowel syndrome, and a prudent nutritional strategy is essential to reduciing the duration of parenteral nutrition and decreasubg the risk of parenteral nutrition-related complications. To facilitate intestinal adaptation, start minimal enteral feeding at the early stage and gradually increase the amount of enteral nutrition according to intestinal tolerance. Oral feeding and a varied and balanced diet are necessary. Breast milk and blended diet are good choices.

Key words: short bowel syndrome, nutrition, feeding strategies, adaptation, parenteral nutrition, enteral nutrition