中国实用儿科杂志

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儿童炎症性肌病规范化治疗及预后

柴毅明a孙利b周水珍a   

  1. 作者单位: 复旦大学附属儿科医院 a神经科, b肾脏风湿科,
  • 出版日期:2014-02-06 发布日期:2014-01-22

Standardized treatment and prognosis children with inflammatory myopathy .       

CHAI Yi-mingSUN Li,ZHOU Shui-zhen.   

  1. Department of Neurology,Pediatrics Hospital Affiliated to Fudan University, Shanghai  201102, China.
  • Online:2014-02-06 Published:2014-01-22

摘要:

儿童炎症性肌病包括感染和免疫相关两类,前者以病毒性肌炎为主,后者以幼年皮肌炎常见。治疗方法根据病因、程度而不同,包括抗感染和免疫治疗,免疫治疗首选激素和免疫抑制剂。是否及时诊治、病损程度、是否合并心肺等器官受累是影响预后的因素。

关键词: 炎症性肌病, 皮肌炎, 多发性肌炎, 幼年, 肌炎

Abstract:

Inflammatory myopathy include, infective myositis and idiopathic inflammatory myopathy. Infective myositis is mostly caused by virus, while juvenile dermatomyositis is the mainly type in idiopathic inflammatory myopathy in children.  Aggressive treatment approaches  include anti-infective and immunotherapy,which depend on pathogeny and the extent of disease.Glucocorticoids and  immunosuppressive are the first choice of immunotherapy. Delay of diagnosis and treatment,acute onset of severe symptoms and the complications are associated with poor outcome.

Key words: inflammatory myopathy, dermatomyositis, polymyositis, juvenile, myositis

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