关键词: 胎盘早剥, 婴儿, 早产, 肝素

Abstract:

Objective    To conclude the clinical characteristics of the late-preterm neonates with placental abruption and to build up the therapeutic protocol. Methods    Retrospective analysis was conducted. According to enrolling qualifications，83 subjects from the hospitalized children of the NICU of Bayi Children’s Hospital Affiliated to General Hospital of Beijing Military Command of PLA were enrolled  from October 2009 to May 2011，in which 37 late-preterm neonates were with placental abruption and 46 late-preterm neonates without placental abruption as the control group included. Results    From clinical manifestations，lab and therapy data，significant differences were detected in gestational age，multiplets，premature rupture of membrane，birth weight，intrauterine growth retardation，mother age，mother gestational diabetes mellitus，asphyxia，APTT，D-dimer on admission，red cell transfusion，plasma transfusion and use of heparin between the observation group and control group （P < 0.05）. Conclusion    Placental abruption is due to placental insufficiency，often resulting in coagulation disorder ； low-dose heparin as well as plasma transfusion can improve neonates’ outcome.

Key words: abruptio placentae； infant, premature； heparin